This content has not been reviewed within the past year and may not represent Web MD's most up-to-date information. To find the most current information, please enter your topic of interest into our search box. 11, 2002 -- Is it safe to treat genital herpes when I'm breastfeeding? That question pops up all the time on the Web MD Genital Herpes message board. And now a new study shows that one commonly used drug, Valtrex, appears to be safe for your child. Genital herpes, caused by the herpes simplex virus, is very common in the U. Currently, about one in every five people has the disease and this number continues to grow, according to the study researchers. Once someone is infected, the virus lives in the body forever. "I have [genital herpes] and my OB has put me on Valtrex for the last four weeks of my pregnancy. First of all, the Valtrex precautions advise not to breastfeed during the use of medication. There are very effective medicines, however, that can treat an outbreak. These medicines can also help keep the virus from reactivating in people who have frequent, repeated outbreaks. Acyclovir was the first drug used for genital herpes. metformin vitamin b12 deficiency The dosage of acyclovir in milk after valacyclovir is less than 1% of a typical infant dosage and would not be expected to cause any adverse effects in breastfed infants. No special precautions are required when using valacyclovir during breastfeeding. PMID: 22509337 393 Information presented in this database is not meant as a substitute for professional judgment. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site. In one study, administration of valacyclovir to mothers with concurrent herpes simplex type 2 and HIV infections reduced breastmilk shedding of the HIV virus in breastmilk at 6 and 14 weeks postpartum, but not later. In another study in HIV-positive mothers, valacyclovir did not reduced breastmilk shedding of cytomegalovirus (CMV) or infant CMV acquisition. Five mothers who were nursing neonates were given valacyclovir 500 mg orally every 12 hours for 5 days. Median peak acyclovir concentrations in milk of 4.2 mg/L occurred at 2 to 4 hours after the first dose and was similar after the last dose. Infant safety during and after maternal valacyclovir therapy in conjunction with antiretroviral HIV-1 prophylaxis in a randomized clinical trial. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The authors calculated the median milk concentration at steady-state to be 2.24 mg/L. The median half-life in milk was 2.1 hours (range 1.3 to 12.2 hours). Using the median milk levels from this study, an exclusively breastfed infant would receive 0.34 mg/kg daily by mouth with this regimen, which is less than 1% of dosage given to neonates. In a study of pregnant women with concurrent HIV and Herpes simplex infections, mothers received zidovudine 300 mg daily from week of pregnancy until 12 months postpartum and nevirapine at delivery. Acyclovir concentrations in human breast milk after valaciclovir administration. Half of the women (n = 74) also received valacyclovir 500 mg orally twice daily from 34 weeks gestation until 12 months postpartum. Is viagra covered by insurance Of acyclovir from breast milk was similar to that for serum. Unchanged valacyclovir was not detected in maternal serum, breast milk, or infant urine. Caution should be exercised when VALTREX ® is administered to a nursing woman. cheap viagra super active 100mg VALTREX is indicated for the treatment of herpes zoster shingles and the. Aciclovir, the principal metabolite of valaciclovir, is excreted in breast milk. Aug 12, 2008. Valtrex tablets contain the active ingredient valaciclovir. The tablets. Valtrex should only be administered to breast-feeding mothers if the. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies have not been performed on the relationship of age to the effects of valacyclovir in children below 12 years of age with cold sores, and children below 2 years of age with chickenpox. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of valacyclovir in the elderly. However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment in the dose of patients receiving valacyclovir. Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. The dose in immunocompromised patients is 1000 mg three times daily for at least seven days (3000 mg total daily dose) and for 2 days following crusting of lesions. This dose should be reduced according to creatinine clearance (see Renal impairment below). For recurrent episodes, treatment should be for three to five days. For initial episodes, which can be more severe, treatment may have to be extended to ten days. For recurrent episodes of herpes simplex, this should ideally be during the prodromal period or immediately upon appearance of the first signs or symptoms. Valtrex can prevent lesion development when taken at the first signs and symptoms of an HSV recurrence. For herpes labialis (cold sores), valaciclovir 2000 mg twice daily for one day is effective treatment in adults and adolescents. The second dose should be taken about 12 h (no sooner than 6 h) after the first dose. Valtrex breast milk Medications and Mothers Milk Online, Valtrex - Medsafe Metoprolol structure Valtrex is the brand name for valacyclovir, an antiviral drug used to treat infections caused by certain types of viruses. Valtrex will pass into breast milk and could harm a nursing infant. Valtrex Valacyclovir - Side Effects, Dosage. VALTREX* Tablets - GSK VALACYCLOVIR - ORAL Valtrex side effects, medical uses, and drug. It is not known whether Valtrex is excreted into breast milk. It is known, however, that among women taking acyclovir, concentrations of acyclovir in breast milk are about four times higher than in the mother's blood. The safety of valacyclovir in zoloft xanax and alcohol Continued. Acyclovir was found in the breast milk. However, the amount seen in the milk was considerably less than that used to treat infants that have been infected with herpes. The herpes virus is not transmitted through breast milk. However, your baby could get infected by touching a blister or sore on your breast, mouth, or other area.