Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquin malaria Hydroxychloroquine allergic reaction This list is not complete and many other drugs can interact with hydroxychloroquine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil medication interactions Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine Plaquenil Chloroquine as antiinflammatoryStopped plaquenil now symptoms have returnedSarafen and plaquenilHydroxychloroquine wiki DRUG INTERACTIONS Acetaminophen; Butalbital; Caffeine; Codeine. Acetaminophen; Caffeine; Dihydrocodeine Moderate Concomitant use of dihydrocodeine. Amitriptyline; Chlordiazepoxide Major Avoid coadministration of hydroxychloroquine. Amoxicillin; Clarithromycin; Lansoprazole. Plaquenil hydroxychloroquine sulfate dose, indications.. Plaquenil - Uses, Side Effects, Interactions -. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil Interactions Explained. The following sections explain in detail the potentially negative interactions that can occur when Plaquenil is combined with any of the drugs listed above. Certain Beta Blockers. Plaquenil may increase the level of some but not all beta blockers in the blood, perhaps increasing the risk of side effects. To make sure hydroxychloroquine is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; heart disease, heart rhythm disorder such as long QT syndrome; diabetes; a stomach disorder; an allergy to quinine; liver or kidney disease; Drug interactions are reported among people who take Plaquenil and Escitalopram together. This study is created by eHealthMe based on reports of 133 people who take Plaquenil and Escitalopram from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008.