Plaquenil (hydroxychloroquine) is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. I started both of these ten weeks ago, I'm on 400mg hydroxy and 25mg of methotrexate. Weiggt gain tryibg to get off plaquenil What is plaquenil used for in lupus I am on both methotrexate and plaquenil. I have been on plaquenil for over a year and a half and methotrexate since September. I have had no side effects from either one. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes used to be every 2 weeks. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. I don't know how I can carry on like this feeling constantly sick and anxious :-( Does it get better? I started both of these ten weeks ago, I'm on 400mg hydroxy and 25mg of methotrexate. Last week I got in such a state about having to take them and it's got to a point where I constantly feel sick because I'm so anxious of having them, so I've been taken off hydroxychloroquine for two weeks so that now I only have medication on a Monday, I thought this would help but the whole afternoon I was feeling nauseuous and now I've taken my weekly dose my stomach is swirling and head is pounding. Hydroxychloroquine & methotrexate Evaluation of efficacy of combination of methotrexate and., Does anyone take methotrexate and hydroxychloroquine. - NRAS Dose of hydroxychloroquineChloroquine is a painless suicideUse of plaquenil for osteoarthritisPlaquenil and oral pigmentationPlaquenil and etoh Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in antigen presentation or effects on the innate immune system. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Hydroxychloroquine Plaquenil. Hydroxychloroquine Uses, Dosage & Side Effects -. Methotrexate - rashes; Does anyone know if hydroxychloroquine and methotrexate can cause weight loss; Does anyone take methotrexate and hydroxychloroquine and has anyone had problems with hydroxychloroquine? Drugs changed from methotrexate to sulphasalazine! Red rash around he eyes due to methotrexate? Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the.