It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Dark palate hydroxychloroquine Macular oct plaquenil toxicity Chloroquine autophagy lc3 Chloroquine phosphate and leather corals Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Dry skin Loss of appetite Abdominal bloating Upset stomach Stomach cramps Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Connie, I have been on Plaquenil for about 5 years now and YEP - I have the "brown" skin discolorations on my face both cheeks and also my arms. It does get darker over the summer and if I stay at 400mg for a long time. I am able to cover up and even out my cheeks with foundation & powder. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and skin changes Hydroxychloroquine DermNet NZ, Hydroxychloroquine Plaquenil Side Effects & Dosage for. Hydroxychloroquine sulfate 200 mg film coated tablets Vision changes/loss of vision There is a chance that retinal damage will occur while taking hydroxychloroquine Plaquenil or chloroquine Aralen. This is called known as hydroxychloroquine retinopathy. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Skin Color Change -. Common and Rare Side Effects for Plaquenil Oral. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Things that happen from MCTD anyway, so I just thought it was a normal flare. I didn't connect it to my diet change until just now. I feel so betrayed. I can't walk well, or run at all. I use a cane and a wheelchair. My joints kill me, my muscles and skin hurt. I'm photosensitive, have to hide from the sun.