It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Can you take prednisone with hydroxychloroquine Hydroxychloroquine toxicity monitoring Hydroxychloroquine increases the QT interval and should not be administered with other drugs known to prolong the QT interval. Ventricular arrhythmias and torsade de pointes TdP have been reported with the use of hydroxychloroquine. Postmarketing data indicate that hydroxyzine causes QT prolongation and TdP. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. However, elderly patients are more likely to have unwanted side effects such as confusion, drowsiness and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving hydroxyzine. Pregnancy This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Hydroxyzine and plaquenil Plaquenil Hydroxychloroquine Side effects, Images, Uses., Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Plaquenil anger Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxyzine Oral Route Before Using - Mayo Clinic. Hydroxychloroquine Oral Route Before Using - Mayo Clinic. Dec 18, 2018 Hydroxyzine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of itching, or hives on the skin. Hydroxyzine may be used to treat allergic skin reactions such as hives or contact dermatitis. Usage Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people.