I have been getting these horrible rashes and they are not related to sun exposure. I am starting to wonder if they are related to Plaquenil. Chloroquine injection in pregnancy Chloroquine resistant p falciparum Plaquenil scalp Prescribed hydroxychloroquine 200 mg twice a day to take in addition to leflunomide. About ten days later, he developed a diffuse pruritic. induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms in relation to the eliciting drug. Immunol Allergy Clin North Am. 2009 Known hypersensitivity to hydroxychloroquine or 4-aminoquinoline Children under six years of age, due to the increased risk of overdose Patients taking tamoxifen as tamoxifen increases the risk of retinopathy Hydroxychloroquine hypersensitivity rash These lysosomotropic effects occur in macrophages, dendritic cells, and lymphocytes. To determine if adverse cutaneous eruptions due to hydroxychloroquine are more common in patients with dermatomyositis than in those with cutaneous lupus erythematosus. I've always been one to go for the natural route and am starting to feel like I should just stop taking everything and see what happens - so frustrating. My doctor now wants me to start on Chloroquine instead of plaquenil. Hydroxychloroquine hypersensitivity rash Hydroxychloroquine Sulfate Hypersensitivity Reports., Hydroxychloroquine DermNet NZ Plaquenil 200 mg pricesHydroxychloroquine deafnessChloroquine dosage sle Hydroxychloroquine Plaquenil is one of the safest drugs in medicine. Serious side effects are rare & routine blood tests are not required. Allergy new skin rashes is unusual but it means ruling our future use. Commoner, usually mild, side effects are indigestion, ‘gurgly tummy’, diarrhoea & headache. Plaqunil rash -. Hydroxychloroquine hypersensitivity rash.. Hydroxychloroquine-induced erythema multiforme. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.