Macular thinning plaquenil

Discussion in 'Northwest Pharmacy Canada' started by almig, 17-Mar-2020.

  1. RDZ Well-Known Member

    Macular thinning plaquenil


    One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

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    Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil-induced maculopathy is a form of retinal toxicity that is associated with long-term use of of the anti-inflammatory medication plaquenil. The drug-induced maculopathy is associated with the following risk factors Cumulative dose level of 1,000 grams of plaquenil; Patients with existing retinal or macular disease; Patients over the age of 60 Aug 29, 2014 The side effect that is of greatest concern is retinal toxicity. Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy.

    It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress.

    Macular thinning plaquenil

    Plaquenil Uses, Dosage & Side Effects -, Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS

  2. Rashes due to hydroxychloroquine
  3. SD-OCT showed loss of the parafoveal inner/outer segment junction, thinning of the parafoveal outer nuclear layer, and a loss of the normal foveal depression, which is characteristic for hydroxychloroquine retinal toxicity Figure 3.

    • Hydroxychloroquine Plaquenil Toxicity and Recommendations..
    • The Risk of Retinal Toxicity with Plaquenil.
    • Hydroxychloroquine toxicity - EyeWiki.

    Peripapillary retinal nerve fiber layer thinning was consistently seen in patients who presented with retinal lesions compatible with antimalarial toxicity. - Selective thinning of the inner retina in the 7 × 7 mm posterior pole was observed in those without clinically-apparent fundus changes. The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. It succinctly makes the case for screening, and Hydroxychloroquine Plaquenil is a disease-modifying antirheumatic drug that is commonly used to reduce arthritic pain and swelling. Signs and symptoms. “The associa­tion of Plaquenil therapy with mac­ular toxicity is well established,” said Michael F. Marmor, MD, at the Byers Eye Institute at Stanford University.

     
  4. 1StRex User

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Chloroquine Oral Route Proper Use - Mayo Clinic Chloroquine Aralen - Side Effects, Dosage, Interactions - Drugs Chloroquine Dosage Guide with Precautions -
     
  5. BuKToP New Member

    Hydroxychloroquine Plaquenil Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness.

    Hydroxychloroquine Side-effects, uses, time to work