Implementation of the guideline’s recommendations will prevent iatrogenic visual loss. The new guideline also makes recommendations regarding the techniques and timing of baseline and follow-up screening tests for both hydroxychloroquine and chloroquine retinopathy. Does plaquenil affect blood pressure Is hydroxychloroquine safe to take while breastfeeding Avoid sun with plaquenil We discuss updated recommendations concerning hydroxychloroquine daily dosing, retinopathy screening, serologic monitoring, use in smokers, use in pregnant women, and adverse effect risk and monitoring. This review can hopefully serve as an aid to dermatologists and help ensure they continue using hydroxychloroquine safely and effectively. The RCOphth guidelines specify the diagnostic tests for screening 10-2 Humphrey visual field testing using a white stimulus, followed by pupillary dilation and imaging with both spectral domain optical coherence tomography and widefield fundus autofluorescence. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. In general, hydroxychloroquine is a safe and cost-effective medication, particularly when compared to newer anti-inflammatory medicines which can more significant adverse effects on the body. Hydroxychloroquine is a medicine that is effective in treating various long-term inflammatory disorders of the joints and skin. Plaquenil monitoring guidelines HYDROXYCHLOROQUINE Shared Care Guideline V1, Monitoring for retinal toxicity in patients taking. Can a pregnant woman take chloroquine Jan 03, 2020 Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base. Plaquenil Dosage Guide -. Hydroxychloroquine DermNet NZ. My Take on New Ocular Screening Guidelines for Plaquenil.. Mar 01, 2011 The new guidelines recommend 10-2 automated perimetry, plus at least one of SD-OCT, FAF, or mfERG if they are available. These tests should be performed at baseline and at each subsequent evaluation. Other tests may be considered as well, but are generally insufficiently sensitive to detect early evidence of hydroxychloroquine toxicity. Some authors recommend 6.5 mg/kg of actual 32 body weight with a cap at 400 mg per day and further adjustments for renal insufficiency 10. 33 To date, there are no data demonstrating that monitoring blood levels of HCQ is useful in dosing 34 HCQ to prevent retinal toxicity. Plaquenil hydroxychloroquine sulfate, Sanofi-Aventis and the less-used chloroquine are antimalarial drugs with anti-inflammatory properties that are used for the management of a spectrum of inflammatory conditions.