All my issues were resolved over a years time on low doses. I believe my problems started with side effects of a statin, which I stopped taking during my Plaquenil treatment but resumed after symptoms were resolved. Is quinolone related to plaquenil Chloroquine tablet Hydroxychloroquine mechanism of action drunkbank Peripheral neuropathy is found among people who take drugs with ingredients of hydroxychloroquine sulfate, especially for people who are female, 60+ old also take medication Methotrexate, and have High blood pressure. Both agents were felt to have a role in her progressive decline, with hydroxychloroquine likely inducing a mild myopathy over the previous 12 months. This worsened acutely with the introduction of colchicine, and her symptoms resolved with discontinuation of both of these agents within 8 weeks. A patient with psoriatic arthritis developed a peripheral neuropathy while taking hydroxychloroquine and naproxen. Although it was initially suspected that hydroxychloroquine was responsible for the neuropathy, subsequent rechallenge with naproxen demonstrated that clinical and electrophysiologic findings were related to routine pharmacologic doses of naproxen. Has anyone had neurological issues resolved with a Plaquenil treatment? I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. Years later I am now having small fiber issues in my hands which I think were triggered by side effect of statins and am looking for solutions. Hydroxychloroquine causing neuropathy Toxic neuropathies, Hydroxychloroquine and Colchicine Induced Myopathy The. Hydroxychloroquine hand osteoarthritisHydroxychloroquine street valueWhat does chloroquine do in transfection PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg administration. Inactive Ingredients Dibasic calcium phosphate USP, hypromellose USP, magnesium stearate NF, polyethylene glycol 400 NF, polysorbate 80 NF, corn starch, titanium dioxide USP, PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Drug‐induced peripheral neuropathy in a patient with psoriatic arthritis. Hydroxychloroquine-Induced Toxic Myopathy Causing.. Peripheral neuropathy is found among people who take Plaquenil, especially for people who are female, 60+ old also take medication Methotrexate, and have High blood pressure. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Muscle biopsy consistently reveals curvilinear bodies and muscle fiber atrophy with vacuolar changes. Most cases manifest as insidious onset proximal myopathy that may be associated with peripheral neuropathy and cardiac myotoxicity. Resolution of symptoms is slow after discontinuation of therapy and may be incomplete.