It typically happens in the evening or nighttime hours when you're sitting or lying down. Restless legs syndrome, also known as Willis-Ekbom disease, can begin at any age and generally worsens as you age. It can disrupt sleep, which interferes with daily activities. No need to check g6pd level for plaquenil Ocular side effects hydroxychloroquine How does hydroxychloroquine work in the body Aao 2016 plaquenil guidelines Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. A rare complication of the commonly used rheumatoid arthritis drug hydroxychloroquine Plaquenil is injury to the retina the light-sensing portion of the back of the eye. The earliest sign of retinal changes from hydroxychloroquine is a decreased ability to distinguish between red and green colors. Medications also help many people with symptoms as abnormal, unpleasant sensations in their legs or feet. They do, however, consistently describe the desire to move their legs. Sometimes, symptoms disappear for periods of time, then come back. Simple self-care steps and lifestyle changes may help relieve symptoms. The sensations, which generally occur within the limb rather than on the skin, are described as: usually don't describe the condition as a muscle cramp or numbness. Plaquenil heavy legs Nighttime Leg Cramps Meds That Hurt, Meds That Help - GoodRx, Plaquenil Uses, Dosage & Side Effects - Hypoglycemia and plaquenil The heat and pain from burning feet syndrome may become more intense at night and may not only involve the soles of the feet, but also the tops of the feet, ankles, and even the lower legs. Burning feet syndrome, also known as Grierson-Gopalan syndrome, is a set of symptoms in which the feet often become uncomfortably hot and painful. Burning Feet Syndrome Grierson-Gopalan Syndrome. Rheumatoid Arthritis 17 Signs of Serious Complications. Plaquenil Oral Uses, Side Effects, Interactions.. This was twice cleared up with heavy doses of antibiotics and Cortisone. However my rheumatologist took me off all arthritis drugs and we added them back little by little. When plaquenil was finally included with the other drugs again, it took about three days and my My face started swelling and the rash and and itching. I have been on 400 mg daily of Plaquenil, last week my doctor took me off of it ue to increase in the pain I had been having in lower back and unbelievable pain in my left leg and especially the extreme pain in the heel of my left foot. It was becoming painful to walk. After 5 days of stopping pain was 80% better. I too have that 'heavy' feeling in my legs where it feels almost as if you won't be able to pick up your feet and so tend to shuffle. Going up steps is very difficult as some days it is easier to move one leg than the other. I don't, however, have to be standing a lot for this to happen.