Hydroxychloroquine lupus nephritis

Discussion in 'Hydroxychloroquine' started by KOSMOS aka Anarion, 07-Mar-2020.

  1. ulka-x XenForo Moderator

    Hydroxychloroquine lupus nephritis


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. -Each dose should be taken with a meal or a glass of milk.

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    Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Mar 04, 2019 Azathioprine is useful in moderate-to-severe lupus nephritis. It improves renal outcome, but it does not appear to be as effective as cyclophosphamide, although it is less toxic. Mycophenolate mofetil is an option for induction therapy with class II/IV lupus nephritis. It has generally been well tolerated and. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus.

    -Concomitant therapy with an 8-aminoquinoline drug is necessary for the radical cure of vivax and malariae malaria. Use: Malaria prophylaxis Acute attack: 800 mg (620 mg base) orally followed in 6 to 8 hours by 400 mg (310 mg base), then 400 mg (310 mg base) once a day for 2 consecutive days; alternatively, a single dose of 800 mg (620 mg base) has also been effective Alternate dosing based on body weight: A total dose representing 25 mg/kg is administered in 3 days, as follows: First dose: 10 mg base/kg (not to exceed 620 mg base) orally Second dose: 5 mg base/kg (not to exceed 310 mg base) orally 6 hours after first dose Third dose: 5 mg base/kg orally 18 hours after second dose Fourth dose: 5 mg base/kg orally 24 hours after third dose Comments: -Each dose should be taken with a meal or a glass of milk.

    Hydroxychloroquine lupus nephritis

    Hydroxychloroquine in Lupus. - ACR Meeting Abstracts, Lupus Nephritis Medication Corticosteroids, Immunosuppressives

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  7. Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis

    • Hydroxychloroquine use predicts complete renal remission..
    • Treating Lupus with Anti-Malarial Drugs Johns Hopkins..
    • A Long-Term Study of Hydroxychloroquine Withdrawal on..

    Lupus nephritis, one of the most serious manifestations of systemic lupus erythematosus SLE, usually arises within 5 years of diagnosis; however, renal failure rarely occurs before American College of Rheumatology criteria for classification are met. Lupus nephritis is histologically evident in most patients with SLE, even those without cl. In this study we have shown that hydroxychloroquine retards the development of renal damage in lupus nephritis patients after adjusting for confounding variables associated with its intake whether proteinuria is omitted from the end-point or not. Kasitanon N, Fine DM, Haas M, et al. Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis.

     
  8. Svyt User

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Immune & Autoimmune - Lupus Lupus and Vaginal itching or rash
     
  9. Disabled Well-Known Member

    Compare Plaquenil vs Chloroquine - Chloroquine needs to be taken 1-2 weeks before traveling to an area with malaria, compared to some alternatives that can be taken 1-2 days before. chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions.

    Chloroquine drug Britannica
     
  10. disbrest Well-Known Member

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