That means the system designed to keep your body healthy mistakenly attacks parts of your body that are vital to everyday function. The protective coverings of nerve cells are damaged, which leads to diminished function in the brain and spinal cord. Hydroxychloroquine reviews sjogren& 39 Plaquenil for rosacea I took Plaquenil for suspected Sjogren's syndrome for over 3 years. It did absolutely nothing for symptoms that evenutally would be diagnosed as MS. This is just my personal experience and you didn't say which connective tissue disease you had so this may not apply to you. Jan 25, 2014 I can't help but wonder if your symptoms are a natural progression of your disease more than a side effect of Plaquenil. If they are just a side effect then it's certainly not worth being on it. There are other meds they can try. Check with the pharmacist tomorrow but please also call your doctor's office next week. Amyotrophic Lateral Sclerosis ALS Signs and Symptoms ALS affects the u pper motor neurons, which are in the brain, and the lower motor neurons, which are in the spinal cord and brainstem. While some people experience fatigue and numbness, severe cases of MS can cause paralysis, vision loss, and diminished brain function. MS is a disease with unpredictable symptoms that can vary in intensity. Does plaquenil ease symptoms of ms and als Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, I am taking plaquenil, 200 ms, once a day. I would like to stop? Oct testing for plaquenilChloroquine emc It's horrible. I have a pile of other MS symptoms that don't seem to be Plaquenil side effects. The other medication that might be causing all my problems is Elavil Amitriptyline. I've taken 20mg of it for years, but my psychiatrist has slowly been increasing it to help with my depression and sleep. MS symptoms. Or is it from the Plaquenil, Elavil? Arg! - Lupus. Diseases - ALS - Signs & Symptoms Muscular Dystrophy.. I am taking plaquenil, 200 ms, once a day. I would like to.. As it happens, many drugs can cause a lichenoid reaction that results in lichen sclerosus, including plaquenil, beta blockers, and even NSAIDs. However, about 9 out of 10 times, plaquenil is effective in *treating* lichen planus, so it's sort of a double-edged sword, with the odds far in favor of. Lichen Planus by American Family Physician for more information. After learning I had MS for years and thinking lots of my symptoms came from disc problems with my back. After MRI & lots of tests I was told I have MS lesions in spine & brain and I also tested positive for Lupus. My point being, I don't take a specific med. for lupus because they always focused on my MS & supposedly the meds. MS Symptom Listing. Individuals with multiple sclerosis MS may experience one or more of a variety of symptoms, possibly affecting individuals physically, emotionally, mentally, psychologically, and/or in ways that others can’t see the “invisible” symptoms of MS. The types and severity of symptoms differ greatly between people with MS.