It’s also referred to as knee instability or weak knees. While it’s often accompanied by pain, this isn’t always the case. Side effects of chloroquine in pregnancy Plaquenil discoid lupus Plaquenil nausea diarrhea Plaquenil contraindications Feb 19, 2020 Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, Muscle weakness can be a symptom of many chronic conditions and acute infections. It can also be a side effect of certain medications. Find out more about the causes of muscle weakness here. Drug-induced muscle weakness Muscle weakness also may be a side effect of certain drugs used to treat lupus and related conditions, including prednisone and other corticosteroids, cholesterol-lowering drugs and hydroxychloroquine Plaquenil®. However, if it keeps happening, it could be a sign of something else. If it’s only happened once or twice, you may have just stumbled. Plaquenil knee weakness Hydroxychloroquine Plaquenil, Muscle weakness 12 causes and more Chloroquine phosphate pronounceChloroquine omeprazolePlaquenil for lupus reviews Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. How Lupus Affects the Muscles, Tendons and Joints Lupus.. PLAQUENIL®. Hydroxychloroquine is used to treat discoid lupus erythematosus DLE or systemic lupus erythematosus SLE or lupus. It is also used to treat acute and chronic rheumatoid arthritis. This medicine is available only with your doctor's prescription. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Take this medication with a meal or a glass of milk to prevent stomach upset. Common side effects include nausea, loss of appetite, headache, and diarrhea. Plaquenil can cause blurred vision and dizziness. Do not drive or operate heavy machinery until you know how it affects you.