It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Makers of plaquenil Patient teaching when taking hydroxychloroquine Aug 26, 2013 Plaquenil hydroxychloroquine is associated with a variety of rashes, and you should discuss with your doctor if a medication change would be the best treatment for your rash. Read more. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight. feeling sick nausea or indigestion. diarrhoea. headaches. bleaching of the hair or mild hair loss. tinnitus ringing in the ears visual problems. TreatmentRisksClinical significanceContraindicationsPreventionResultsBenefitsPrognosis For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil for skin rash Plaquenil Hydroxychloroquine - Side Effects, Dosage., Hydroxychloroquine Side-effects, uses, time to work Drug of choice for chloroquine resistant malariaLong term use hydroxychloroquineMethotrexate plaquenilMethotrexate vs plaquenil side effects long term Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Treating Lupus with Anti-Malarial Drugs Johns. Will you have Rashes with Plaquenil - eHealthMe. Side effects include nausea, vomiting, diarrhea, hemolysis destruction of red blood cells in G6PD deficient patients patients low in this enzyme are more likely to break down red cells as a reaction to Plaquenil, visual abnormality uncommon, discoloration of skin bluish-gray, vertigo, weakness, and irritability. Pigmentary changes in skin and mucous membranes, bleaching of hair, and alopecia are usually reversible when therapy is discontinued.-AGEP should be distinguished from psoriasis, although this drug may precipitate attacks of psoriasis; it may be associated with fever and hyperleukocytosis. Common 1% to 10% Rash, pruritus Sep 13, 2019 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.