Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Is plaquenil an nsaid Retinal changes with plaquenil In summary, if you have Sjögren’s, hydroxychloroquine may be an option to help your symptoms. Because there are other more effective therapies available to treat dry eyes and dry mouth, it is typically prescribed to help musculoskeletal pain and fatigue. Be patient, as the drug may take up to 6 months to see a beneficial effect. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Other cutaneous adverse reactions of hydroxychloroquine have also been reported Table-1 11–16, 22. Two out of the seven reported cases of hydroxychloroquine induced cutaneous adverse reactions were fatal. In our case, the patient’s skin lesions resolved with high dose and slow taper course of steroid treatment. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine skin rash treatment Hydroxychloroquine Skin Support, Hydroxychloroquine Plaquenil Hydroxychloroquine sarcoidosis dosagePlaquenil capsule appearanceEarly oct changes plaquenil Mar 17, 2019 An overdose of hydroxychloroquine can be fatal, especially in children. Take hydroxychloroquine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. When treating lupus or arthritis, tell your doctor if your symptoms do not improve after 6 months of treatment. Hydroxychloroquine Uses, Dosage & Side Effects -. Hydroxychloroquine-induced erythema multiforme. Plaquenil Side Effects Common, Severe, Long Term -. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Deficiency Of Granulocytes A Type Of White Blood Cell. Rash from Methotrexate or Hydroxychloroquine. rheumy who has now stopped all my treatment,so as you can imagine I am in complete irony is the. Rashes, Skin Care and Cutaneous Lupus What You Should Know. Rashes, Skin Care and Cutaneous Lupus What You Should Know. Rashes, Skin Care and Cutaneous Lupus What You Should Know. Adapted from a presentation at the SLE Workshop at Hospital for Special Surgery. it is not common and sometimes hard to separate from other types of skin rashes.