Many people find that they have unexplained bruising on legs and want to know what causes bruises to appear for no apparent reason. Some people also bruise more easily than others and a seemingly insignificant knock may leave a black and blue dark patch on their skin. Plaquenil does increase liver enyzmes Que es el medicamento plaquenil Chloroquine lysosome fusion Plaquenil alternatives uctd I've started to get really tender shins and bruising for no reason on my legs. I've seen my gp and they are miffed and have done some blood tests. I have alot of fatigue and my legs feel heavy, im on plaquenil and nifidipine for raynauds. has anyone else had this? Plaquenil tablets contain the active ingredient hydroxychloroquine, which is a type of medicine called a disease-modifying anti-rheumatic drug DMARD. unexplained bruising or bleeding, purple. Oct 22, 2019 Low blood cell counts have happened with Plaquenil hydroxychloroquine. If blood cell counts get very low, this can lead to bleeding problems, infections, or anemia. Call your doctor right away if you have signs of infection like fever, chills, or sore throat; any unexplained bruising or bleeding; or if you feel very tired or weak. For example, being in the sun too long, aging, or a vitamin deficiency can weaken small blood vessels near the skin’s surface. Random or unexplained bruising on legs can happen for a number of reasons. Plaquenil and unexplained bruising Plaquenil Oral Uses, Side Effects, Interactions, Pictures., Plaquenil hydroxychloroquine Diamondback chloroquine phosphateAmerican academy of ophthalmology plaquenil guidelinesWhat exactly does plaquenil doPlaquenil and ibuprophenChloroquine exocytosis However, if these unexplained bruises begin to appear on the legs quite frequently, then there may be an underlying ailment that could be disrupting your circulation. This is especially concerning if your bruises take an especially long time to heal after they appear. Causes of Unexplained Bruising on Legs What Causes Unexplained Bruises to Appear on Your Legs? MD.. Plaquenil Indications, Side Effects, Warnings -. When to Report Reactions to Plaquenil. Bruising is common with long term steroid use. Spotted Trout Syndrome I like to call it. How did that get there? A common comment from mates. As long as the bruises heal all good. If bruises linger or enlarge best to go to doctor to sort as an infection can occur. Be careful. Be well. On on on. Nov 09, 2018 Sporadic bruising usually isn't cause for worry. Oftentimes, you can reduce your risk for future bruising by making sure you're getting the right nutrients in your diet. Read on to learn more. Hydroxychloroquine-induced pigmentation lesions usually begin after a few months or years of treatment. When we compared our patients with the controls, we found no significant association with the duration of HCQ treatment or with the cumulative dose of HCQ.