Chloroquine resistant malaria drug of choice

Discussion in 'Generic & Brand Canadian Pharmacy' started by edgy, 21-Feb-2020.

  1. starik Guest

    Chloroquine resistant malaria drug of choice


    According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance.

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    Mefloquine Lariam —This is the treatment of choice for travel to most regions of sub-Saharan Africa and other areas with high levels of chloroquine -resistant malaria parasites. Like chloroquine, the medication is taken once a week, from one to two weeks before departure until four weeks after your return. Recognition of the value of chloroquine was delayed, and it was not brought forward until it was reevaluated in the United States and designated the drug of choice against malaria near the end of World War II. Chloroquine quickly proved to be one of the most successful and important drugs ever deployed against an infectious disease. ANSWER Chloroquine-resistant malaria has been observed in India and so the first line drug of choice should be an artemisinin-derivative in combination with another drug this group of medications are more generally known as "artemisinin-based combination therapies" or ACTs.

    These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine).

    Chloroquine resistant malaria drug of choice

    Medicines for the Prevention of Malaria While Traveling., Chloroquine-Resistant Malaria The Journal of Infectious.

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  7. In addition, any of the regimens listed above for the treatment of chloroquine-resistant malaria may be used for the treatment of P. malariae and P. knowlesi infections. P. vivax and P. ovale Chloroquine or hydroxychloroquine remains an effective choice for all P. vivax and P. ovale infections except for P. vivax infections acquired in Papua New Guinea or Indonesia.

    • CDC - Malaria - Diagnosis & Treatment United States..
    • Chloroquine-Resistant Malaria –.
    • Chloroquine - Prescription Drug Information..

    Chloroquine is the drug of choice for the prophylaxis and treatment of sensitive malaria species during pregnancy. Chloroquine should only be given during pregnancy when need has been clearly established. See references. Chloroquine Breastfeeding Warnings. Chloroquine is excreted into human milk. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug. Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link Traditionally, chloroquine has been the first line drug of choice for uncomplicated, non-resistant malaria. However, several types of malaria, and most notably Plasmodium falciparum, the most severe and deadly kind, has become resistant to chloroquine in many places.

     
  8. Andrey1 New Member

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. What is Chloroquine Phosphate? - GoodRx Aralen Chloroquine Uses, Dosage, Side Effects, Interactions, Warning WHO Model Prescribing Information Drugs Used in Parasitic Diseases.
     
  9. telemad XenForo Moderator

    This can be a result of increases to muscle mass, increases in body fat, or increases in body fluids like water. Plaquenil Side Effects on Your Eyes and Vision Plaquenil and weight gain - Plaquenil & Weight Gain/Loss -
     
  10. bUFF Moderator

    Chloroquine phosphate C18H32ClN3O8P2 - Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase.

    Chloroquine - FDA prescribing information, side effects and uses