Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Retinal changes with plaquenil Hydroxychloroquine suppress immune system Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine -sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Side effects, drug interactions, pregnancy safety information, and dosage information should be reviewed prior to taking this medication. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Information on plaquenil medication Plaquenil Disease Interactions -, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Chloroquine rxlistAralen dose To make sure Plaquenil is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; heart disease, heart rhythm disorder such as long QT syndrome; diabetes; a stomach disorder; an allergy to quinine; liver or kidney. Plaquenil Uses, Dosage & Side Effects -. Plaquenil Side Effects Common, Severe, Long Term -. Hydroxychloroquine Oral Route Description and Brand Names.. Jan 03, 2020 PLAQUENIL is indicated for the treatment of uncomplicated malaria due to P. falciparum, P. malariae, P. ovale, and P. vivax. PLAQUENIL is indicated for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Limitations of Use in Malaria PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL.