Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil and effexor Can plaquenil cause low wbc Ra hydroxychloroquine Discontinuing plaquenil Cyclosporine and cyclosporine modified are also sometimes used to treat Crohn's disease a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever and to prevent rejection in patients who have received pancreas or cornea transplants. Plaquenil may decrease the level of some parasite medications in the blood, possibly making them less effective. Check with your healthcare provider before taking these medications together. Cyclosporine. Plaquenil may increase the level of cyclosporine in your blood, which can be quite dangerous. Learn about drug interactions between cyclosporine oral and hydroxychloroquine oral and use the RxList drug interaction checker to check drug combinations. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Cyclosporine and plaquenil Plaquenil vs. Prednisone Prescription Treatment for., Drugs That Can Interfere With Plaquenil Malaria chloroquine tabletsHydroxychloroquine dosage rheumatoid arthritis Hydroxychloroquine sulfate Plaquenil ® can potentially interact with a few other medications. Some of these medicines that may lead to hydroxychloroquine drug interactions include Certain beta blockers, such as Bisoprolol Zebeta ® Metoprolol Lopressor ®, Toprol XL ® Propranolol Inderal ® Sotalol Betapace ® Drug Interactions With Hydroxychloroquine. Cyclosporine oral and hydroxychloroquine oral Drug.. Cyclosporine MyLupusTeam. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Summary Immunodeficiency disorders is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months, also take medication Humira, and have Mixed connective tissue disease. Cyclosporine has been shown to be effective in severe unremitting urticaria that has had a poor response to conventional treatment with antihistamines. Cyclosporine 3-5mg/kg/day appears to benefit about two-thirds of patients with chronic urticaria who do not respond to antihistamine.