Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Can plaquenil cause pancreatitis Can you take hydroxychloroquine with percosets Effectiveness of chloroquine in malaria The authors found that those on leflunomide at time of surgery had a statistically significant increased risk of infection during wound healing P=0.01 26. With the conflicting numbers regarding wound healing complications, their recommendation was to wash out leflunomide using cholestyramine in adults with RA 1 week before surgery 17,20. I just had major spine surgery in November. The surgeon had me check with my rheumy about stopping Plaquenil and I was told to continue it, or just stop it the day of surgery then get right back on, I asked what would happen if I stopped for a week and was told I'd risk going into a flare. I stayed on it and surgery went OK. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil surgery healing Stopping Plaquenil before surgery Lupus Forums at The Lupus., Stopping Plaquenil before surgery Lupus Forums at The. Plaquenil side effects neuropathyChloroquine mechanism mitochondriaPlaquenil dosage for osteoarthritis Aug 19, 2013 In the absence of clear guidelines for the care of patients with rheumatic diseases undergoing orthopedic surgery, management must be individualized to bring favorable patient outcomes, reduction in hospital stay, and maximum utilization of resources. Perioperative Management of Patients with Rheumatic Diseases. Hydroxychloroquine Plaquenil. Recovery from surgery with MCTD DailyStrength. I looked back through my lab work. Even while taking 400mg of Plaquenil and 15mg of Prednisone also an immunosuppressant, my immune system was still overactive. My Absolute Neutrophils good indicator of immune system function didn't get suppressed to a NORMAL range until I increased the Plaquenil to 600mg/day while still taking the Prednisone. Most of the medications used for treatment of RA have potential toxicities, though Plaquenil is widely believed not to add significant risk to surgery and to wound healing. The lower the prednisone dose, the better. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight.