I started Plaquenil last week and so far the side effects are dizziness, nausea and tummy feeling weird. I was just wondering has long it takes to adjust and if taking twice the dose will result in higher discomfort. Maculopathy from plaquenil Hydroxychloroquine metabolism cyp I currently take plaquenil, azathioprine, and 2 BP nerd 1 prescribed for migraines years before lupus dx. Lately, I’ve been experiencing extreme itchiness, almost painful sometimes. It lasts for almost an hour after I’m out of the shower. I’m thinking it’s related to the azathioprine because it didn’t start until after I started it. Symptoms can start to improve in one to two months, but it may take up to six months before the full benefits of this medication are experienced. Side Effects Hydroxychloroquine typically is very well tolerated. Then, 6.5 mg per kg of body weight taken 6 hours, 24 hours, and 48 hours after the first dose. However, dose is usually not more than 800 mg for the first dose and not more than 400 mg for the next doses. Children—Dose is based on body weight and must be determined by your doctor. Also, any tips on how to keep up with taking them on schedule? I have to take Plaquenil, Naturethroid and Vitamin D, everyday . I'm having lots of trouble falling asleep (been having it for a while), not sure if it's getting worse due to the pills. How longbto take plaquenil after alcohol Hydroxychloroquine Side-effects, uses, time to work, Hydroxychloroquine Plaquenil Multifocal erg plaquenil toxicityAralen onlineWhat kind of medicine is mefloquine chloroquine primaquine and quinine According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Will you have Alcohol interaction with Plaquenil - eHealthMe. If you're taking Plaquenil for an autoimmune condition, your symptoms should begin to improve after a few months, but it can take up to six months for full effects. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects. It may take up to six months before the full benefits of Plaquenil are realized. Dosage The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more.