It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Teva-chloroquine effets secondaires Plaquenil and vasculitis Is plaquenil an nsaid drug Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. If you are taking hydroxychloroquine over a long duration, it is important to take eye exams every 6 to 12 months. 6 Do not take hydroxychloroquine if you experience vision symptoms, including problems seeing or reading, light sensitivity, blurred distance vision, or light flashes or streaks. Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long does it take plaquenil to start working Hydroxychloroquine Side Effects, Dosage, Uses, and More, Hydroxychloroquine Plaquenil - Sketchypharm hydroxychloroquineChloroquine cocktail with valium and zopiclone Most people say about 6 months. It works over time. It's pretty suttle. One day all the sudden you will notice that your arms or legs or feet don't feel as bad as they used to. Not that it is a cure all but it usually does help. How long until Plaquenil started working?. Plaquenil -. Plaquenil Uses, Dosage & Side Effects -. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works. Depending on how full your stomach it codine should take 20 min to a hour to work. Symptoms can start to improve in one to two months, but it may take up to six months before the full benefits of this medication are experienced.