It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Allergic reaction when changed from hydroxychloroquine to plaquenil Hydroxychloroquine dosage for malaria prevention Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. May 21, 2010 I have had the same on my forearms but one spot disappeared after a year. I'm not sure how or why it did but I was glad, it just looked like a dark circle on my arm. I am not if my heritage has anything to do with it Native American, but the Plaquenil does make me extremely photosensitive. Of course it lightens some in the Winter months. Plaquenil belongs to a class of medication often called as disease-modifying antirheumatic drugs known as DMARDs. Antimalarials are used in changing the way your immune system works. Plaquenil medication reduces skin problems in lupus and prevents swelling or pain in arthritis. However, it is still not known exactly how the drug works. Side Effects For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Does plaquenil make your skin dark Plaquenil and spots on skin DailyStrength, Plaquenil & skin discoloration - Does going off plaquenil cause fever after surgeryHydroxychloroquine for osteoarthritisAralen dosage for lupusHow expensive is plaquenil per pill Does any one else have a problem with a foul smelling body odor or thier urine being dark colored and having a foul odor with lupus? I am also diabetic so it could possibly come from that also. Its just very hard to deal with and makes me so concious to be around other people. I also have. Body odor with Lupus? DailyStrength. Common Side Effects of Plaquenil. Lupus-Specific Skin Disease and Skin Problems Johns Hopkins.. Apr 18, 2009 I decided to try laser skin therapy for the sun spots, and that's helping fade them. The Plaq is doing so much to help me, there's no way I'll stop taking it even with the facial discoloring. You may find decreasing your dose to 200 mg. will make the SJS symptoms worse. I don't want to risk it. Oct 11, 2004 I am not aware of any eye color changes occurring from Plaquenil. Skin changes though occur in 3-10% of people taking Plaquenil. This may take the form of a rash or slight change in skin or hair pigment. The skin pigment change is rare but can look like a suntan. Plaquenil can make fair-skinned people more sensitive to sunburn. Feb 19, 2020 Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.