The main finding in scleroderma is thickening and tightening of the skin and inflammation and scarring of many body parts, leading to problems in the lungs, kidneys, heart, intestinal system and other areas. Twins and family members of those with scleroderma or other autoimmune connective tissue diseases, such as lupus, may have a slightly higher risk of getting scleroderma. There is still no cure for scleroderma, but effective treatments for some forms of the disease are available. Children can also develop scleroderma, but the disease is different in children than in adults. Best alternative to plaquenil for lupus Hydroxychloroquine sulfate 200 mg price Plaquenil and eye problems Plaquenil help migraine Jan 22, 2016 I was 55 when diagnosed with "CREST" in 2000 & started on Plaquenil & a since withdrawn NSAID. My early symptoms in addition to abnormal labs were severe fatigue, joint pain mainly in lower body - legs & hips, reflux & Raynauds. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. CREST syndrome, also known as the limited cutaneous form of systemic sclerosis lcSSc, is a multisystem connective tissue acronym "CREST" refers to the five main features calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. A great deal of research is also underway to find better treatments for scleroderma and, hopefully, someday a cure. Although the underlying cause is unknown, promising research is shedding light on the relationship between the immune system and scleroderma. Hydroxychloroquine for crest syndrome Scleroderma, Hydroxychloroquine MedlinePlus Drug Information Plaquenil icd9Does plaquenil compromise the immune systemSide effects hydroxychloroquine sulfate 200 mgEasy bruising plaquenil An estimated 25 to 40 percent of those with CREST syndrome will develop calcinosis cutis after 10 years. The lesions usually appear around fingers and elbows and may break open and leak a thick. Calcinosis Cutis Treatment, Diagnosis, Causes, and Symptoms. CREST syndrome - Wikipedia. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. For months now my skin has been thickening I have now reached the point where I feel as though my arms are going to split like a sausage and been extremely inflamed and painful. A month ago I started on Plaquenil and prednisolone. It has helped a bit with the inflammation but on reading various. What is CREST syndrome? CREST Syndrome is a form of scleroderma that is characterized by least two of the following symptoms calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia. Common symptoms reported by people with CREST syndrome Limited scleroderma can affect your skin, digestive tract, heart, lungs or kidneys. Treatment focuses on managing symptoms and preventing complications.