It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil and rheumatoid nodules Hydroxychloroquine hair loss Mar 17, 2019 Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Hydroxychloroquine Sulfate is a synthetic derivative of quinolyl with chemotherapeutic and antibiotic properties, Hydroxychloroquine Sulfate acts against erythrocytic malarial parasites Plasmodium vivax, ovale, and malariae by concentrating in food vacuoles. It inhibits plasmodial heme polymerase and acts through other unknown mechanisms. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine sulfate lupus Plaquenil and Sulfa Allergies" Lupus Community - Support Group, Hydroxychloroquine - Wikipedia Plaquenil and ivfWhat does plaquenil do to your eyesightPlaquenil eye screening guidelinesHydroxychloroquine sulfate solubility Irreversible retinal damage observed in some patients who had received hydroxychloroquine sulfate; significant risk factors for retinal damage include daily doses of hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate and concurrent macular disease Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine sulfate C18H28ClN3O5S - PubChem. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus Center. Oct 30, 2019 Hydroxychloroquine sulfate salt 200 mg is equivalent to hydroxychloroquine base 155 mg. Dermatomyositis, cutaneous disease off-label use Note Used in combination with antipruritic medications, topical therapy, and nonpharmacologic measures eg, photoprotection Miller 2019; Vleugels 2019. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is C 18 H 26 ClN 3 O. H 2 SO 4. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration.