In certain countries and parts of the world where malaria is still present, a person can easily catch malaria from a seemingly insignificant mosquito bite. These medications are primarily designed to treat the strains of malaria linked with mosquito bites, but there are a few alternate uses for these medications outside the scope of treating malaria infections. Hydroxychloroquine and lupus pregnancy Eye screening for plaquenil Plaquenil tablet omhuld 200mg Some strains of P. falciparum are resistant to chloroquine and hydroxychloroquine. Chloroquine resistance is widespread. Chloroquine should not be used for treatment of P. falciparum infections from areas of chloroquine resistance or malaria occurring in patients where chloroquine prophylaxis has failed. Medicines for the Prevention of Malaria While Traveling Hydroxychloroquine Plaquenil™ What is hydroxychloroquine? Hydroxychloroquine also known as hydroxychloroquine sulfate is an arthritis medicine. that also can be used to prevent malaria. It is Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. It belongs to a disease-modifying antirheumatic drug classification. Combined with other medications, hydroxychloroquine is often used as part of a treatment plan for a host of auto-immune diseases, such as rheumatoid arthritis and lupus. Malaria hydroxychloroquine resistance WHO Responding to antimalarial drug resistance, Medicines for the Prevention of Malaria While Traveling. Plaquenil maximum dosage for lupusChloroquine diphosphate 25 μmPlaquenil muscle pain Multi-drug resistant malaria In areas of Thailand near the borders with Cambodia and Myanmar and in Western Cambodia, P. falciparum infections do not respond to chloroquine or pyrimethamine-sulfadoxine, and sensitivity to quinine is reduced. Treatment failures of over 50% are also being reported. Malaria Prophylaxis – Malaria Site. Hydroxychloroquine MedlinePlus Drug Information. DailyMed - HYDROXYCHLOROQUINE SULFATE tablet, film coated. Chloroquine Aralen and Hydroxychloroquine Plaquenil Chloroquine phosphate or hydroxychloroquine sulfate can be used for prevention of malaria only in destinations where chloroquine resistance is not present see Maps 2-7 and 2-8 or the next section in this chapter, Malaria Risk Information and Prophylaxis, by Country. Hydroxychloroquine is an antimalarial drug used to prevent and treat malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. PLAQUENIL is not recommended for the treatment of complicated malaria. PLAQUENIL is not effective against chloroquine or hydroxychloroquine-resistant strains of Plasmodium species see CLINICAL PHARMACOLOGY - Microbiology. PLAQUENIL is not recommended for the treatment of malaria acquired in geographic areas where chloroquine resistance occurs.