It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and prednisone will i lose weight or gain weight Chloroquine torsades Plaquenil birth control affects Can you get high off hydroxychloroquine sulfate Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. Leflunomide, a disease-modifying anti-rheumatic drug DMARD. Apr 13, 2005 The Combination of Leflunomide Arava and Methotrexate is Safe & Efficacious for the Treatment of Rheumatoid Arthritis. Methotrexate MTX, an anti-metabolite that inhibits purine pathways, has been the hallmark of standard of care for many years in the treatment of rheumatoid arthritis RA. Leflunomide is predicted to moderately increase the clearance of caffeine citrate. Manufacturer advises monitor and adjust dose. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Interactions with plaquenil and leflunomide Leflunomide Arava, The Combination of Leflunomide Arava. - Arthritis Information Hydroxychloroquine sulfate side effectsHydroxychloroquine prescribing informationPlaquenil eval icd 10Hydroxychloroquine cause yellow sweat stainsPlaquenil ibd Arava Drug Interactions. If certain medications are taken with Arava, drug interactions may occur. These reactions can alter the amount of the medications in your blood, potentially increasing your risk for side effects or decreasing the effectiveness of the medications. Some of the products that may cause problems with Arava include certain. Arava Drug Interactions - Arthritis Home Page. Leflunomide Interactions BNF content published by NICE. Leflunomide Side-effects, uses, time to work. Leflunomide is the generic form of the brand-name medicine Arava, which is used to treat rheumatoid arthritis a condition in which the body attacks its own joints. This prescription medication. The doctor then kept me on my plaquenil and added Leflunomide Arava to replace the methotrexate. My mouth sores went away and I quit having the days of sickness from the methotrexate. There may be something better out there, but for me the Arava has made a big difference. Summary Drug interactions are reported among people who take Arava and Hydroxychloroquine sulfate together. This study is created by eHealthMe based on reports of 1,199 people who take Arava and Hydroxychloroquine sulfate from Food and Drug Administration FDA, and is updated regularly.