Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Hydroxychloroquine methotrexate drug interactions What can you take instead of plaquenil Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. Hydroxychloroquine risk Hydroxychloroquine and Risk of Development of Cancers, Hydroxychloroquine Plaquenil Chloroquine primaquine babesia forumPlaquenil and pulmonary hypertension Aug 30, 2011 Upon the detection of the visual field defects, the hydroxychloroquine was stopped. She was taking hydroxychloroquine 5.0 mg/kg/day with a duration of 10 years with a cumulative dose of 1460g putting her at increased risk for hydroxychloroquine retinal toxicity. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Recommendations on Screening for Chloroquine and.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Other risk factors include high dose both daily dose and cumulative dose, an age greater than 60 years, and renal or hepatic dysfunction 1. Patients with a history of retinopathy or pre-existing maculopathy should not be treated with hydroxychloroquine. Hydroxychloroquine has a lower risk of ocular toxicity, both corneal and retinal, compared with chloroquine. Smoking possibly reduces the efficacy of hydroxychloroquine, although studies have not usually confirmed this clinical impression. Hydroxychloroquine is considered safer than chloroquine during pregnancy and lactation. Aug 29, 2014 One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur.