It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. How chloroquine icauses itch Benadryl and plaquenil INDICATIONS AND CLINICAL USE PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. Incidence not known. Blistering, peeling, loosening of the skin. blurred vision or other vision changes. chest discomfort, pain, or tightness. cough or hoarseness. dark urine. decreased urination. Hydroxychloroquine is used widely for the treatment of systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatologic conditions. It is now being considered for new applications in diabetes mellitus, heart disease, and adjunct cancer therapy. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine indications Plaquenil hydroxychloroquine sulfate dosing, indications., Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Plaquenil side effects stomach painHydroxychloroquine side effects heart ef 25Plaquenil high blood pressure Research into the wide-ranging effects of hydroxychloroquine has revealed many important benefits in the treatment of lupus; it must be noted that these benefits may be less effective in people who smoke Arthritis Care & Research 2010; 3–400. Benefits include Decrease in the number of disease flares. Drug spotlight on hydroxychloroquine Lupus Foundation of.. Recommendations on Screening for Chloroquine and.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Hydroxychloroquine levels can be measured in the blood. This can potentially be used for monitoring the patient's adherence to treatment and where the response has been inadequate. No standardised effective reference level has been validated. Retinal abnormalities or new vision problems including the inability to distinguish between colors can indicate toxicity and should be discussed immediately with the consulting ophthalmologist. Hydroxychloroquine use in children younger than 7 may be limited by the difficulty in obtaining satisfactory evaluation of color vision in this age group.