Literature review of chloroquine syrup

Discussion in 'Canadian Pharmaceuticals Online' started by yurime, 09-Mar-2020.

  1. ContentMaster New Member

    Literature review of chloroquine syrup


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    How Patients Take Malaria Treatment A Systematic Review of the Literature on Adherence to Antimalarial Drugs. Article Literature Review. to chloroquine syrup, while Denis et al. 1998. Chloroquine is extensively distributed into body tissues, including the placenta and breast milk, and has an enormous total apparent volume of distribution. Some 60% of chloroquine is bound to plasma proteins, and the drug is eliminated slowly from the body via the kidneys, with an estimated terminal elimination half‐life of 1–2 months. The literature review assessed the existing knowledge about the supply and use of paediatric medicines, in general, and the 38 medicines on the global and supplementary lists of children’s. namely, syrup chloroquine, which is no longer used, and paracetamol syrup.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Literature review of chloroquine syrup

    Effects of chloroquine on viral infections an old drug., Therapy of uncomplicated malaria in children a review of.

  2. Chloroquine malaria resistance
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  4. Syrup contains 50 mg/5 mL of chloroquine base equivalent to 80 mg/5 mL of chloroquine phosphate. Chloroquine doses for the treatment and prophylaxis of malaria in BNF publications may differ from those in product literature. A review group convened by the Royal College of Ophthalmologists has updated guidelines on screening.

    • CHLOROQUINE Drug BNF content published by NICE.
    • A Desk Review of Existing Literature on Medicines for Children.
    • Chloroquine - Wikipedia.

    Chloroquine cardiomyopathy – a review of the literature Ernst Tönnesmann Department of Internal Medicine, Kaiser-Karl-Klinik BonnGermany Correspondence [email protected], Reinhard Kandolf Institute for Pathology, University Hospital Tübingen TübingenGermany & Thorsten Lewalter Isar Heart Center Munich MunichGermany Ansah et al. 2001 conducted an RCT of chloroquine tablets for children compared to chloroquine syrup, while Denis et al. 1998 evaluated videos and posters as community health education strategies to improve adherence to a 7-day regimen of quinine + tetracycline. Systematic review of the extent of chloroquine resistant P. vivax and the different methodologies used to quantify therapeutic efficacy. One of the major threats to malaria control and elimination efforts is the ongoing spread and emergence of resistance towards commonly used antimalarial drugs to treat P. falciparum and P. vivax infections.

     
  5. Flock User

    Plaquenil, hydroxychloroquine (HCQ), is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory and autoimmune diseases. RA and Your Eyes Complications Rheumatoid Arthritis. Rheumatoid Arthritis and Eye Health Complications to Watch. Hydroxychloroquine Plaquenil Toxicity and Recommendations.
     
  6. UFO XenForo Moderator

    Chloroquine-resistant Plasmodium falciparum accumulate significantly less chloroquine than susceptible parasites, and this is thought to be the basis of their resistance. Chloroquine Mechanism of action and resistance in malaria 2. Malaria Dissecting chloroquine resistance - ScienceDirect Molecular mechanisms involved in chloroquine resistance.
     
  7. BrandShift Well-Known Member

    Despite Plaquenil dosing recommendations, retinal toxicity. AAO revised guidelines. The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight.

    My Take on New Ocular Screening Guidelines for Plaquenil.
     
  8. Fur Guest

    Protecting your eyesight when taking Plaquenil Lupus. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily

    Will you have Weight increased with Plaquenil - eHealthMe