Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. When plaquenil doesn t work Plaquenil side effects gas Plaquenil joint pain Plaquenil special considerations I went to my rheumy appt and after 1hr 45 min later all had agreed it was the plaquenil. The strange thing is it had only affected the r eye. And yes i did have a baseline eye exam in oct before i started and then this one after experiencing the pain and pressure. HCQ is cleared by the kidneys and thus renal disease increases the risk of toxicity. Therefore, both dosage and screening frequency may need to be adjusted. Tamoxifen use used in breast cancer treatment increases the risk of toxicity approximately 5 fold 8. The mechanism of this linkage is not understood. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and eye pain The Risk of Retinal Toxicity with Plaquenil, Hydroxychloroquine Plaquenil Toxicity and. Hydroxychloroquine and tonic waterBuy plaquenil onlineMetabolism of chloroquinePlaquenil for adenomyosis Plaquenil Hydroxychloroquine is used to dampen inflammation in some forms of arthritis, especially rheumatoid arthritis and lupus. Plaquenil is usually used for long term disease control, rather than in the short term to control active bursts of inflammation. Plaquenil & Your Eyes. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine toxicity - EyeWiki. Talk to your doctor about this, but my guess is that the Plaquenil is not doing anything to cause the pain, but rather that it is not doing enough to prevent it. It sounds like your RA has probably gotten a bit out of control, relative, to your current treatment, and Plaquenil is not a particularly potent drug when it comes to managing joint pain. Many people take Plaquenil for many years without any ill effects. The eye issues they are careful to warn about are actually very rare, and are even reversible, so as long as you get the appropriate eye exam once a year the risk is very, very small. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.