The reaction can be phototoxic and/or photoallergic. Phototoxic reactions result from direct damage to tissue caused by light activation of the photosensitising agent, whilst photoallergic reactions are a cell-mediated immune response in which the is the light-activated photosensitising agent. Plaquenil maculopathy visual field Doxycycline and plaquenil together Plaquenil sulfate 200 mg Feb 19, 2020 PLAQUENIL should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Dermatologic Effects. Dermatologic reactions to PLAQUENIL may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis. A doctor suspects a photosensitivity reaction when a rash appears only in areas exposed to sunlight. A close review of the person's medical history, skin symptoms, any diseases, drugs taken by mouth, or substances applied to the skin such as drugs or cosmetics may help a doctor pinpoint the cause of the photosensitivity reaction. Jun 12, 2018 Phototoxic reactions in skin Acute phototoxicity often begins as an exaggerated sunburn reaction with erythema and edema that occurs within minutes to hours of light exposure. Vesicles and bullae may develop with severe reactions. Although some oral photosensitising medications can cause photoallergic reactions, most cause phototoxic reactions. Photoallergic reactions occur less commonly than phototoxic reactions and are mostly caused by photosensitising topical agents. Phototoxic reaction to plaquenil Will you have Photosensitivity reaction with Plaquenil - eHealthMe, Photosensitivity Reactions - Skin Disorders - Merck Manuals Consumer. Plaquenil urticarial vasculitisPlaquenil and lexaproHow does plaquenil help autoimmune diseasesAre there withdrawal symptoms from plaquenil The reaction induced by psoralens, for the most part, is nonphotodynamic. Acute phototoxic reactions are characterized by erythema and edema followed by hyperpigmentation. Long-term ultraviolet phototoxicity results in chronic sun damage and skin cancer formation. Phototoxicity and photoallergy.. Drug-Induced Photosensitivity Clinical Presentation History.. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Sep 11, 2014 There are two types of drug-induced photosensitive reactions phototoxic reactions and photoallergic reactions. Phototoxic reactions require large amounts of exposure to both the chemical and ultraviolet light. The reaction resembles an exaggerated sunburn and can occur quickly, within minutes or hours of exposure. Phototoxic reactions will only appear on sun-exposed skin, however the less common photoallergic reactions can spread to unexposed areas. Apr 10, 2019 Plaquenil side effects. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Phototoxic reaction This is the most common reaction and usually occurs when a drug you’re taking whether by mouth or topically applied is activated by exposure to UV light and causes damage to the skin that can look and feel like a sunburn or a rash.