Act or chloroquine malaria

Discussion in 'Canadian Pharcharmy Online' started by mozie, 05-Mar-2020.

  1. Act or chloroquine malaria


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    For chloroquine-resistant vivax malaria, Amodiaquine 30 mg base/kg bw divided over 3 days as 10 mg/kg bw single daily doses combined with primaquine should be given. Where ACT has been adopted as the first-line treatment for P. falciparum malaria, it may also be used for P. vivax malaria in In areas where chloroquine-resistant P. vivax has been identified, infections should be treated with an ACT, preferably one in which the partner medicine has a long half-life. With the exception of artesunate + sulfadoxine-pyrimethamine AS+SP combination, all ACTs are effective against the blood stage infections of P. vivax. ACTs are, in many cases, the first line treatment for malaria. There are several different types of ACTs. Examples include artemether-lumefantrine Coartem and artesunate-amodiaquine. Each ACT is a combination of two or more drugs that work against the malaria parasite in different ways. Chloroquine phosphate.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Act or chloroquine malaria

    Will the quinine in tonic water prevent malaria? – The., WHO Overview of malaria treatment

  2. Apo-hydroxychloroquine 2oomg
  3. Nov 26, 2014 Artemisinin combination therapy ACT is recommended as first-line treatment for uncomplicated falciparum malaria 4. It is considered for traveller’s malaria and P. knowlesi in endemic areas, whereas chloroquine CQ is still the standard drug for P. vivax, P. malariae and P. ovale in most countries 5.

    • Efficacy and safety of artemisinin combination therapy ACT..
    • Malaria - Diagnosis and treatment - Mayo Clinic.
    • Artemisinin-based combination therapy ACT for treating..

    Non-ACT Treatments for Drug-Resistant Malaria Although ACT is recognized as the best option for treating uncomplicated malaria, non-ACT treatments can still play a role in some instances. The most notable example is the combination of AQ and sulfadoxine-pyrimethamine AQ-SP, which was a promising combination therapy before ACTs became more widely available. ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U. S. Federal Government. Uncomplicated malaria is defined as symptomatic malaria with no life-threatening manifestations. Treatment of choice is Artemisinin-based Combination Therapy ACT. The use of ACT is recommended at various levels home, community, primary health care centres, secondary & tertiary health institutions in Nigeria; What are ACTs

     
  4. gskwillie User

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil Uses, Dosage & Side Effects - Is chloroquine the same as quinine – Humpty Dumpty Grass Valley Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.
     
  5. Ant0nV Guest

    Plaquenil Oral Interactions with Other Medication Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in.

    Nortriptyline oral and mirtazapine oral Drug Interactions.