Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. What otc meds can be taken with plaquenil Chloroquine rxlist Plaquenil bradycardia How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr. Plaquenil is also an option for those who try and fail biologic drugs, cannot tolerate biologics or fear potential side effects linked to biologic DMARDs. How It Works Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Weiggt gain tryibg to get off plaquenil Plaquenil Side Effects Common, Severe, Long Term -, Rx Side Effects New Plaquenil Guidelines and More. Plaquenil and eye exams I happen to run out of my medication and fail to be in a hurry to get a refill because I had convinced myself that it wasn't working anyway. After about 4 day of being off Plaquenil I quickly realized that it in deed was helping. I was at work and at the end of my day I proceeded to walk to my car and could barley raise my legs to walk. Stopping plaquenil. DailyStrength. Taking Plaquenil for Rheumatoid Arthritis. Going off Plaquenil - Sclero Forums MAIN - Sclero Forums. My husband has IBS and doesn't have weight loss or problems gaining weight. Considering my daughters have CD though, I suppose it is a good idea to go ahead with the scopes. If they don't find anything, and I try going off the Plaquenil, what alternatives are there? How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.