Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Chloroquine for dogs Chloroquine concentration lysosome Hydroxychloroquine and coffee Chloroquine resistant malaria usmle PLAQUENIL with drugs known to induce retinal toxicity, such as tamoxifen, is not recommended. Careful ophthalmologic examination should be more frequent and adapted to the patient, in the following situations - daily doses exceeding 6.5 mg salt form/kg ideal lean body weight. Absolute body Plaquenil Examination. Plaquenil is a drug routinely prescribed for rheumatoid arthritis and lupus. Plaquenil has long been associated with retinal toxicity which can lead to vision loss. In particular it affects the macular region of the retina which is responsible for central vision. As a result, all patients taking plaquenil should have an examination approximately every six months. The macula should be examined through a dilated pupil. The incidence of Plaquenil related macular problems increases when approaching a dose of 600 to 700 mg. per day. The average dose is 400 mg. per day. This is a very safe dose. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Ophthalmologic examination plaquenil Plaquenil Eye Exams - Catalina Eye Care, Plaquenil Examination - McKinney Eye Works Plaquenil ocular testingAao hydroxychloroquine guidelinesWhat are the side effects of discontinuing plaquenilPaludrine chloroquineUsing plaquenil in end stage macular degeneration If you take Plaquenil, it is very important to see an ophthalmologist regularly. Your ophthalmologist will check your retina for problems before serious damage occurs. Next What Is Plaquenil? - American Academy of Ophthalmology. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Plaquenil therapy and eye exams. - Eye Care - MedHelp. Hydroxychloroquine use in children younger than 7 may be limited by the difficulty in obtaining satisfactory evaluation of color vision in this age group. Therefore, children taking HCQ should receive an annual ophthalmologic examination. Other rare side effects include changes in skin pigmentation and cardiomyopathy diseases of the heart muscle. For women, start with 100 pounds, and add 5 pounds for every inch over 5 feet. For men, start with 106 pounds, and add 6 pounds for every inch over 5 feet. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. HCQ retinopathy is typically asymptomatic in patients who are in the early stages of the disease, according to a 2015 study published in the Indian Journal of Ophthalmology by Hemang K. Pandya, MD.