Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil malaria prevention Plaquenil lupus medicine Hydroxychloroquine ayuda a bajar de peso Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Talk to your doctor about this, but my guess is that the Plaquenil is not doing anything to cause the pain, but rather that it is not doing enough to prevent it. It sounds like your RA has probably. Taking plaquenil gave me moderate relief from the joint pain. I only stopped taking it because my primary physician would not keep prescribing it; she insisted that I should see the rheumatologist regularly. I could no longer afford to see him or the other specialists I was seeing. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil lyme joint pain Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Plaquenil and pain" Rheumatoid Arthritis Community. Hydroxychloroquine side effects nhs Specifically, anti-malarial medications have shown to improve muscle and joint pain, skin rashes, pericarditis inflammation of the lining of the heart, pleuritis inflammation of the lining of the lung, and other lupus symptoms such as fatigue and fever. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. PLAQUENIL Side Effects, Reviews by Patients -. LymeMD Plaquenil alone?. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. The symptoms of second stage, early disseminated, Lyme disease can be difficult to attribute. Symptoms include severe fatigue, fever, pain, intermittent weakness and achiness of the muscles and joints, numbness in arms and legs, vision changes, and cognitive dysfunction such as short-term. Plaquenil was great for the pain and swelling but did almost nothing for the fatigue. I actually have found nothing for fatigue. Of all the meds, Plaquenil was the best for me and helped the most, but some people don't tolerate it.