Please review the following URL and make sure that it is spelled correctly. I have been on the plaquenil 200 mgm for about 4 months now. Hydroxychloroquine liver talks A drug that for rumatoid hydroxychloroquine Plaquenil and essential oils Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Plaquenil is the devil! Worked well 1st 2 mts. After that I had issues with my vision, felt waves of nervousness, and extreme anxiety where I started to question my sanity. Hallucinated, broke out in rashes and crying spells. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. Causes for plaquenil to stop working What next if plaquenil doesn't work? -, Plaquenil oral Reviews and User Ratings Effectiveness, Ease. Easy bleeding plaquenilDoes plaquenil help sclerodermaPilocarpine hydroxychloroquine 5 mg tabletHypnozoite chloroquine resistancePlaquenil ra forum Mar 24, 2011 Had headaches with the plaquenil so went to the sulfar and predisone. Sulfar was a waste of time and since I had a little help from the plaquenil he switched me back to that with pain meds for the headaches and body. Recently i went back for app. and plaquenil had stopped doing anything so he added the methotrexate to it. I did not want to take it. What next if plaquenil doesn't work?. Plaquenil - Uses, Side Effects, Interactions -. Hydroxychloroquine Plaquenil. One of the problems with Plaquenil is that because it's so slow to act, the improvements are also slow and subtle. So most people don't realize that they've improved until they STOP taking it. I've been on it twice, along with Atabrine another antimalarial. In my case, it never worked so I didn't notice a change. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes.