It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Shortness of breath related to plaquenil Plaquenil and bone loss Do chloroquine cause splenomegaly A Consumer Reports Health prescription drugs survey reported that many people are splitting their pills in half to save money on high-priced prescription drugs. The bad news, however, is that many have also learned to save even more money by taking half-doses of half-a-pill every other day. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil prescribed by rheumatologist cut in half Cutting Pills in Half Could Pose Problems, Plaquenil hydroxychloroquine sulfate dosing, indications. Plaquenil and swollen lymph nodesPotential adverse effect with hydroxychloroquineHydroxychloroquine and metforminChloroquine schedule Is anyone taking liquid Plaquenil Hi, Is anyone out there taking Plaquenil in liquid form for rheumatoid arthritis. I can't swallow the Plaquenil pills - I've cut them in half and then quarters but the jagged edges scratch my throat going down and I've tried applesauce, putting butter on them, and other things. Bone Joint Muscle - Arthritis Is anyone taking liquid Plaquenil. Plaquenil Dosage Guide - - Prescription Drug.. Hydroxychloroquine Could Cut Recurrence of Congenital Heart.. Diverticulitis is #170 concern in Plaquenil discussions. Plaquenil is an arthritis medication and an anti infectious agent. Uses Plaquenil is prescribed for Lupus, RA, Sjogren's Syndrome and Joint Pain and is mostly mentioned together with these indications. Now I have a question to ask you Plaquenil users. I have a vague memory when my Rheumatologist first prescribed Plaquenil that he told me I could take two pills at one time or split the doses. I was very timid about starting this med so choose to split the doses. The problem is I work a maximum stress job. Stress and eating do not mix with me. The mean plasma elimination half-life varied, depending on the post-administration period, as follows 5.9 hours at C max-10 hours, 26.1 hours at 10-48 hours and 299 hours at 48-504 hours. The parent compound and metabolites are widely distributed in the body and elimination is mainly via the urine, where 3% of the administered dose was recovered over 24 hours in one study.