It can decrease the pain and swelling of arthritis, prevent joint damage, and reduce the risk of long-term disability. You should not take it if you have a sulfa allergy. Sulfasalazine is used in the treatment of rheumatoid arthritis (RA), inflammatory bowel disease, and some other autoimmune conditions. Sulfasalazine comes in a 500mg tablet and should be taken with food and a full glass of water to avoid an upset stomach. Plaquenil mefloquine What helps nausea from plaquenil Chloroquine preparation Plaquenil hydroxychloroquine and Azulfidine EN-tabs sulfasalazine delayed release tablets are used to treat rheumatoid arthritis. Plaquenil is also used to treat or prevent malaria, and to treat symptoms of discoid or systemic lupus erythematosus. Azulfidine EN-tabs is also used to treat moderate to severe ulcerative colitis. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. May 28, 2016 I have been diagnosed with Limited Scleroderma. My choices are Methotrexate, Plaquenil or Sulfasalzine Azulfidine. I researched them and determined Plaquenil would be my last choice, although it was his first, because I already have lattice degeneration of the retina in both eyes and one of the potential side effects is retinal problems. After the first week, the dose may be slowly increased to the usual dosage of two tablets (1g) twice a day. The medication is often started at low doses when treating RA to prevent side effects, typically one - two tablets a day. Sulfasalazine plaquenil Sulfasalazine Oral Route Side Effects - Mayo Clinic, Hydroxychloroquine Plaquenil Chloroquine kaufenChloroquine bootsDmards plaquenilChloroquine overdoseMethotrexate and hydroxychloroquine Sulfasalazine is a DMARD. DMARDs work to decrease pain and inflammation, reduce/prevent joint damage, and preserve joint mobility. So, Sulfasalazine treats swelling, pain, and stiffness in inflammatory arthritis. However, it is not entirely clear how this medication works for RA. What are the long term effects of taking sulfasalazine.. Methotrexate, Plaquenil or Sulfasalazine Azulfidine.. Compare Plaquenil vs Sulfasalazine -. If the plaquenil is helping and they say you need it, I'd take it - the side effects will go away. I've not had experience with sulfasalazine - but from what I've read, the side effects of that med are about the same as those of plaquenil. BTW - sulfasalazine is an anti-inflammatory. ANSWER Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild rheumatoid arthritis. They are not as powerful as other disease-modifying antirheumatic drugs, but they. However, hydroxychloroquine has an extremely favorable toxicity profile and is widely considered to be safe to use in the perioperative period as it is not a potent immunosuppressant. Leflunomide, sulfasalazine, and azathiaprine all have immunosuppressive properties and can be toxic at high levels.