I'm not completely pain free, but it's a lot better than it was. I've been on plaquenil since mid June I have had a lot of stress in my life so I can't determine what is causing what. Not seeing any improvements with pain but I just went to 0 prednisone 3 weeks ago. said give it a few months and if I don't see any improvement I might as well go off of it. Wanted to let you know that I was on plaquenil for about three years and I told my RA doctor that my fatigue was worse. It just seems like the fatigue is worse than it has ever been, and it doesn't seem to matter if I go to bed early or take a nap during the day. Woke up and cleaned the kitchen an hour later(my kitchen is a galley kitchen 8 ft maybe.no time) Took a nap. Early on I did get those stomach cramps and diarrhea. All my pain is tolerable and he sees no deformities so he says he doesn't see RA activity. Just because the pain is tolerable doesn't make me like it any better. He did a plaquenil test and sure enough it was low. Acid reflux and plaquenil What is the nursing intervention for hydroxychloroquine Accidentally inhaled hydroxychloroquine sulfate 200 mg I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness. Experts aren’t certain what causes the fatigue of lupus. In some patients it may be caused by fibromyalgia, a syndrome of widespread muscle pain and fatigue. About one-third of people with. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. I wake up tired in the morning, get my kids fed and off to the schoolbus, and some days that's all I can do until it's time to go pick them up and make dinner, then I collapse after the kids are put to bed. I don't know if this is just the way RA is, or if it is a side effect of the medicine. Wasn't going to eat luch because I would have to move to do it.husband bought out. Kids came home, helped with homewrok, made dinner..picked up couch(because my blanket and pillow were there) Went to bed at 9. Plaquenil lupus fatigue Will you have Fatigue with Plaquenil - eHealthMe, Fighting Lupus Fatigue and Boosting Energy Plaquenil drug manufacturer Nov 16, 2018 Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. Exercise and iron infusions have done the brunt of the work. Things that Changed My Life with Lupus Fatigue, Part 3. Hydroxychloroquine Plaquenil. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil hydroxychloroquine "Started taking Plaquenil 5 days ago for bad butterfly rash caused by dermal lupus. I’m extremely dizzy, bad stomach pain, ringing in the ears, etc. I’m extremely dizzy, bad stomach pain, ringing in the ears, etc. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. If anything, it’s Lupus OR psychosomatic. Plaquenil is a slow-acting drug which is why you take it long term. It honestly takes on average 1 to 3 months to work and be built up in your system, which is why you typically have a 3-6 month review after being prescribed it.