Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine yellow skin Prednisone for plaquenil Ra drug plaquenil Hydroxychloroquine 20 mg Initial dose 400 mg 310 mg base orally once or twice a day for several weeks or months, depending on patient response Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Each dose should be taken with a meal or a glass of milk. Usual Pediatric Dose for Malaria Treatment of the acute attack 1 year or older First dose 10 mg base/kg Initial dose 400 mg 310 mg base orally once or twice a day for several weeks or months, depending on patient response Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Each dose should be taken with a meal or a glass of milk. One Plaquenil tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take Plaquenil with a meal or a glass of milk. Malaria. Prophylaxis Adults 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil 400 mg once a day Ideal time for taking Plaquenil and side effects? Lupus., Hydroxychloroquine Uses, Dosage & Side Effects - Malaria chloroquine primaquine and chloroquine phosphatePlaquinil hydroxychloroquine If you are also taking a certain drug for diarrhea kaolin or taking antacids such as magnesium /aluminum hydroxide, take hydroxychloroquine at least 4 hours before or after these products. These products may bind with hydroxychloroquine, preventing your body from fully absorbing it. Use this medication. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Plaquenil - FDA prescribing information, side effects and uses. Taking Plaquenil for Rheumatoid Arthritis. Initial dose 400 to 600 mg 310 to 465 mg base orally once a day to optimum response usually 4 to 12 weeks -Maintenance dose 200 to 400 mg 155 to 310 mg base orally once a day Dose adjustment The dose may need to be reduced temporarily if adverse side effects occur; after 5 to 10 days the dose may gradually be increased to the optimum. Jan 18, 2019 People weighing more than 135 lbs. will stay within the safety guidelines not more than 6.5mg/kg/day at 400mg per day but people under 135lbs. should probably only be taking 200 mg per day. Other risk factors for Hydroxychloroquine retinal toxicity include kidney or liver disease and obesity. Standard dosing 400 mg once a week on the same day of each week starting 2 weeks before traveling to an area where malaria occurs, and continued for 4 weeks after leaving the area. Weight-based dosing Dose is based on body weight and must be determined by your doctor.